MRCOOL Signature Series 4 Ton Multi-Position Air Handler | MCAEAMPEF48E21AA
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Summary
The MRCOOL® Signature Series 48k Multi-Position Air Handler is a powerful and flexible solution for year-round home comfort. Engineered for performance and efficiency, this system works with R-454B refrigerant, offering a more environmentally friendly option that meets modern energy standards without compromising reliability. Designed to adapt to your space, this air handler supports upflow, downflow, and horizontal installations, making it an ideal fit for a wide range of home layouts. When you're dealing with limited space, its compact and streamlined design makes installation easy without sacrificing capacity. The cabinet exterior is outfitted with galvanized steel built to withstand wear, along with an interior ECM blower motor that delivers steady airflow while helping reduce energy consumption. The copper "A" coils and aluminum fins provide efficient heat transfer, while thermal insulation along the inside of the cabinet helps reduce condensation accumulation and improve overall system efficiency. Setup is straightforward, cutting down on labor time and cost. Maintenance is just as simple, thanks to the air filter rack, and an optional electric heat kit is available for enhanced heating in colder regions. For added convenience, this system pairs effortlessly with most third-party smart thermostats, giving you full control over your comfort without being tied to a specific platform. Backed by a 10-year limited parts warranty, the MRCOOL® Signature Series 48k Multi-Position Air Handler delivers reliable, efficient comfort season after season.
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Important
AHRI certified - meets industry standards. Register your product to activate warranty coverage. This air handler contains R-454B refrigerant, which is classified as an A2L refrigerant. To comply with safety standards, this unit must be paired with an R-454B condenser equipped with a leakage detection system. Failure to comply with these requirements may result in safety hazards and could void the warranty.
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Key Features
- 48,000 BTU capacity (4 Ton)
- Multi-position installation (upflow, downflow, horizontal)
- Environmentally friendly R-454B refrigerant
- High-efficiency ECM blower motor
- Quiet operation (57 dBA)
- Durable galvanized steel cabinet
- Copper "A" coils with aluminum fins
- Built-in air filter rack for easy maintenance
- Compatible with most third-party smart thermostats
- Optional electric heat kit available
- Internal thermal insulation
- AHRI certified
- 5-speed blower motor for precise airflow control
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Complete Technical Specifications
| Brand | MRCOOL |
| Series | Signature Series Multi-Position Air Handler |
| Model | MCAEAMPEF48E21AA |
| UPC | 840255595896 |
| GTIN | 00840255595896 |
| Unit Type | Air Handler |
| Configuration | Multi-Position |
| Certifications | UL Listed, CSA Listed, ETL Listed, AHRI Certified |
| Capacity | 48,000 BTU (4 Ton) |
| CFM | 1549 |
| Refrigerant | R-454B |
| Electrical | 208/230V 1 Phase 60 Hz |
| Min Circuit Ampacity | 7.2A |
| Max Fuse Breaker | 10A |
| Blower Motor Type | ECM |
| Blower Motor HP | 3/4 |
| Blower Motor Speeds | 5 |
| Blower Motor RPM | 1010 |
| Sound Rating | 57 dBA |
| Liquid Line Size | 3/8" |
| Suction Line Size | 7/8" |
| Drain Connection Size | 3/4" |
| Filter Type | Replaceable |
| Filter Size | 20" x 24" x 1" |
| Metering Device | Orifice |
| Auxiliary Heater Included | No |
| Auxiliary Heater Available | Yes (5kW, 7.5kW, 10kW) |
| Net Dimensions (HxWxD) | 53.125" x 22" x 24.5" |
| Net Weight | 163 lbs |
| Shipping Dimensions | 54.89" x 27.75" x 25.2" |
| Shipping Weight | 183 lbs |
Performance Features
| Compatible Equipment | Signature Series Top Discharge Condensers |
| Installation Flexibility | Multi-position (upflow, downflow, horizontal) |
| Refrigerant | Environmentally friendly R-454B refrigerant |
| Motor Technology | High-efficiency ECM blower motor |
| Noise Reduction | Quiet operation (57 dBA) |
| Coil Technology | Copper "A" coils with aluminum fins |
| Cabinet Construction | Durable galvanized steel |
| Speed Control | 5-speed motor for precise airflow adjustment |
| Airflow Capacity | High-capacity 1549 CFM for maximum performance |
| Smart Home Compatibility | Works with most third-party smart thermostats |
| Heating Options | Optional electric heat kits (5kW, 7.5kW, 10kW) |
Warranty Information
- Registered Warranty: 10 years parts, limited lifetime compressor
- Base Warranty: 10 years parts, limited lifetime compressor
- Registration may be required for full warranty coverage
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Manuals & Certifications
Safety Information
PROPOSITION 65 WARNING: This product contains chemicals known to the State of California to cause cancer and birth defects or other reproductive harm.
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Advanced Technology
The MRCOOL Signature Series 48k Multi-Position Air Handler features advanced ECM motor technology with a powerful 3/4 HP motor that delivers superior energy efficiency and precise airflow control across five speed settings. The copper "A" coils with aluminum fins provide exceptional heat transfer and humidity control for optimal indoor comfort in large residential and light commercial applications. The durable galvanized steel cabinet ensures long-lasting performance, while comprehensive thermal insulation minimizes energy loss and prevents condensation. Operating at 57 decibels, this 4-ton air handler maintains reasonable noise levels despite its substantial 1549 CFM airflow capacity. The ECM motor's intelligent operation automatically adjusts airflow to maintain optimal system performance, while compatibility with most third-party smart thermostats enables seamless integration into modern home automation systems for complete comfort control.
Installation Advantages
This 4-ton air handler provides exceptional installation versatility with true multi-position capability for upflow, downflow, or horizontal configurations, making it ideal for various residential and light commercial applications. The high-efficiency ECM motor delivers superior performance with lower energy consumption while handling the substantial 1549 CFM airflow requirement for large spaces. The built-in air filter rack with larger 20" x 24" x 1" filter simplifies routine maintenance. The unit's larger cabinet accommodates the increased capacity while maintaining a streamlined design that minimizes installation time and labor costs. Multiple optional electric heat kit sizes (5kW, 7.5kW, or 10kW) provide flexible heating capacity for various climate requirements. With its enhanced capacity and comprehensive compatibility with Signature Series Top Discharge Condensers, this air handler represents a premium, energy-efficient solution for HVAC systems requiring robust performance in large homes and demanding commercial applications.
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We will prepare your order within 24 hours if it’s received on a weekday (before noon). Orders are shipped in one to two business days. Transit time is between 3 to 6 business days, although exceptions apply. We email tracking information once your purchase is shipped.
Delivery Map

IMPORTANT DELIVERY INFORMATION: Please be kindly informed that this air conditioner, due to its weight and shipping restrictions, is shipped palletized with an arranged freight service and requires an appointment for delivery. To AVOID delays, please check if the provided phone number in the order details is a current number where you can be reached. You can also contact the carrier directly and refer to your tracking number to set up a date and time for your appointment. It is your responsibility to ensure a safe and secure environment for delivery. Please note that we cannot be held liable for any packages that are stolen or lost after delivery has been confirmed. PLEASE verify your shipping address, as changes to the address after freight has shipped can result in an additional 15% or higher fee depending on freight weight and dimensions.
SMALLWARES INFORMATION: Please be informed that for smaller items, such as Installation Kits, Smart Connectivity Dongles, and TTW Sleeves, when these items are ordered individually, they may be shipped via FedEx without a signature requirement. It is your responsibility to ensure a safe and secure environment for delivery. Please note that we cannot be held liable for any packages that are stolen or lost after delivery has been confirmed. Thank you for your understanding and cooperation.
INSPECT YOUR MERCHANDISE BEFORE SIGNING: Please inspect your boxes thoroughly when you receive them. They should arrive shrink-wrapped and on a pallet. If you notice any damages or imperfections (e.g. crushed box or forklift hole), please write comments on the receipt before signing for delivery, no matter how small damages seem. Contact us immediately to assist you.
Shipping & Delivery
We will prepare your order within 24–48 hours if it’s received on a weekday (before noon). Orders are shipped in one to two business days. Transit time is between 3 to 6 business days, although exceptions apply. We email tracking information once your purchase is shipped.
Delivery Map
IMPORTANT DELIVERY INFORMATION
Please be informed that this air conditioner, due to its weight and shipping restrictions, is shipped palletized with an arranged freight service and requires an appointment for delivery.
To AVOID delays, please make sure the phone number in your order details is accurate and one where you can be reached. You may also contact the carrier directly using your tracking number to schedule your delivery.
It is your responsibility to ensure a safe and secure delivery environment. We are not liable for any packages that are stolen or lost after delivery is confirmed.
Please verify your shipping address carefully. Changes to your shipping address after the freight has been shipped may result in additional fees of 15% or more, depending on freight weight and dimensions.
SMALLWARES INFORMATION
Smaller items such as Installation Kits, Smart Connectivity Dongles, and TTW Sleeves may be shipped via FedEx without a signature requirement if ordered individually.
It is your responsibility to ensure a safe delivery location. We are not liable for packages lost or stolen after delivery confirmation. Thank you for your understanding and cooperation.
INSPECT YOUR MERCHANDISE BEFORE SIGNING
Please inspect your boxes carefully upon delivery. Shipments should arrive shrink-wrapped and on a pallet. If you notice any damage or signs of mishandling (such as a crushed box or forklift puncture), write comments on the delivery receipt before signing, even if the damage appears minor.
Contact us immediately if any issues arise so we can assist you promptly.
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